tRNAscan-SE was designed to make rapid, sensitive searches of genomic sequence feasible using the selectivity of the Cove analysis package. We have optimized search sensitivity with eukaryote cytoplasmic and eubacterial sequences, but it may be applied more broadly with a slight reduction in sensitivity .


This tool requires FASTA format.


tRNAscan-SE: A Program for Improved Detection of Transfer RNA Genes in Genomic Sequence.
T.M. Lowe and S.R. Eddy.
Nucleic Acids Research (1997) 25 (5): 0955-964.
The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs.
P. Schattner, A.N. Brooks and T.M. Lowe.
Nucleic Acids Research (2005) 33 (suppl 2): W686-W689.